Towards the detection of copy number variation from single sperm sequencing in cattle

BACKGROUND: Copy number variation (CNV) has been routinely studied using bulk-cell sequencing. However, CNV is not well studied on the single-cell level except for humans and a few model organisms. RESULTS: We sequenced 143 single sperms of two Holstein bulls, from which we predicted CNV events usin...

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Detalles Bibliográficos
Autores principales: Yang, Liu, Gao, Yahui, Oswalt, Adam, Fang, Lingzhao, Boschiero, Clarissa, Neupane, Mahesh, Sattler, Charles G., Li, Cong-jun, Seroussi, Eyal, Xu, Lingyang, Yang, Lv, Li, Li, Zhang, Hongping, Rosen, Benjamin D., Van Tassell, Curtis P., Zhou, Yang, Ma, Li, Liu, George E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928590/
https://www.ncbi.nlm.nih.gov/pubmed/35300589
http://dx.doi.org/10.1186/s12864-022-08441-8

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