Effect of CYP2C19 genetic polymorphism on the pharmacodynamics and clinical outcomes for patients treated with ticagrelor: a systematic review with qualitative and quantitative meta-analysis

BACKGROUND: Studies show inconsistent results regarding the impact of CYP2C19 genotype on the pharmacodynamics (PD) and clinical outcomes of ticagrelor. With the implementation of genotype-guided individualized antiplatelet therapy, the association between CYP2C19 polymorphism and the efficacy and s...

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Detalles Bibliográficos
Autores principales: Xie, Qiufen, Xiang, Qian, Liu, Zhiyan, Mu, Guangyan, Zhou, Shuang, Zhang, Zhuo, Ma, Lingyue, Gong, Yanjun, Jiang, Jie, Cui, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928616/
https://www.ncbi.nlm.nih.gov/pubmed/35300607
http://dx.doi.org/10.1186/s12872-022-02547-3

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