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Chrysoeriol suppresses hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes and inhibits JAK2/STAT3 signaling

BACKGROUND: Fibroblast-like synoviocytes (FLS) have cancer cell-like characteristics, such as abnormal proliferation and resistance to apoptosis, and play a pathogenic role in rheumatoid arthritis (RA). Hyperproliferation of RA-FLS that can be triggered by the activation of interleukin-6/signal tran...

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Detalles Bibliográficos
Autores principales: Wu, Jia-Ying, Chen, Ying-Jie, Fu, Xiu-Qiong, Li, Jun-Kui, Chou, Ji-Yao, Yin, Cheng-Le, Bai, Jing-Xuan, Wu, Ying, Wang, Xiao-Qi, Li, Amy Sze-man, Wong, Lut Yi, Yu, Zhi-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928618/
https://www.ncbi.nlm.nih.gov/pubmed/35296317
http://dx.doi.org/10.1186/s12906-022-03553-w