Gene signature associated with resistance to fluvastatin chemoprevention for breast cancer

BACKGROUND: Although targeting of the cholesterol pathway by statins prevents breast cancer development in mouse models, efficacy is not absolute. Therefore, the goal of this study is to investigate if the upregulation in the cholesterol biosynthesis pathway genes associates with response to statin...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Anjana, Embury, Matthew D., Ju, Zhenlin, Wang, Jing, Bedrosian, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928625/
https://www.ncbi.nlm.nih.gov/pubmed/35296281
http://dx.doi.org/10.1186/s12885-022-09353-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928625/
https://www.ncbi.nlm.nih.gov/pubmed/35296281
http://dx.doi.org/10.1186/s12885-022-09353-2

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