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Gene signature associated with resistance to fluvastatin chemoprevention for breast cancer
BACKGROUND: Although targeting of the cholesterol pathway by statins prevents breast cancer development in mouse models, efficacy is not absolute. Therefore, the goal of this study is to investigate if the upregulation in the cholesterol biosynthesis pathway genes associates with response to statin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928625/ https://www.ncbi.nlm.nih.gov/pubmed/35296281 http://dx.doi.org/10.1186/s12885-022-09353-2 |