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Short open reading frames (sORFs) and microproteins: an update on their identification and validation measures

A short open reading frame (sORFs) constitutes ≤ 300 bases, encoding a microprotein or sORF-encoded protein (SEP) which comprises ≤ 100 amino acids. Traditionally dismissed by genome annotation pipelines as meaningless noise, sORFs were found to possess coding potential with ribosome profiling (RIBO...

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Detalles Bibliográficos
Autores principales: Leong, Alyssa Zi-Xin, Lee, Pey Yee, Mohtar, M. Aiman, Syafruddin, Saiful Effendi, Pung, Yuh-Fen, Low, Teck Yew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928697/
https://www.ncbi.nlm.nih.gov/pubmed/35300685
http://dx.doi.org/10.1186/s12929-022-00802-5

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