Conventional Therapies Deplete Brain-Infiltrating Adaptive Immune Cells in a Mouse Model of Group 3 Medulloblastoma Implicating Myeloid Cells as Favorable Immunotherapy Targets

Medulloblastoma is the most common childhood brain cancer. Mainstay treatments of radiation and chemotherapy have not changed in decades and new treatment approaches are crucial for the improvement of clinical outcomes. To date, immunotherapies for medulloblastoma have been unsuccessful, and studies...

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Detalles Bibliográficos
Autores principales: Abbas, Zahra, George, Courtney, Ancliffe, Mathew, Howlett, Meegan, Jones, Anya C., Kuchibhotla, Mani, Wechsler-Reya, Robert J., Gottardo, Nicholas G., Endersby, Raelene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928748/
https://www.ncbi.nlm.nih.gov/pubmed/35309309
http://dx.doi.org/10.3389/fimmu.2022.837013

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