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DOT1L affects colorectal carcinogenesis via altering T cell subsets and oncogenic pathway

Chronic inflammation and oncogenic pathway activation are key-contributing factors in colorectal cancer pathogenesis. However, colorectal intrinsic mechanisms linking these two factors in cancer development are poorly defined. Here, we show that intestinal epithelial cell (IEC)-specific deletion of...

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Detalles Bibliográficos
Autores principales:	Sun, Danfeng, Wang, Weichao, Guo, Fangfang, Pitter, Michael R., Du, Wan, Wei, Shuang, Grove, Sara, Vatan, Linda, Chen, Yingxuan, Kryczek, Ilona, Fearon, Eric R., Fang, Jing-Yuan, Zou, Weiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928792/ https://www.ncbi.nlm.nih.gov/pubmed/35309733 http://dx.doi.org/10.1080/2162402X.2022.2052640

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