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Host immune response mediates changes in cagA copy number and virulence potential of Helicobacter pylori
Helicobacter pylori is the major risk factor for gastric cancer. H. pylori harboring the type IV secretion system (T4SS) and its effector CagA encoded on the cag pathogenicity Island (cagPAI) increases the risk. H. pylori PMSS1 has a multi-cagA genotype, modulating cagA copy number dynamically from...
Autores principales: | Jang, Sungil, Hansen, Lori M., Su, Hanfu, Solnick, Jay V., Cha, Jeong-Heon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928821/ https://www.ncbi.nlm.nih.gov/pubmed/35289715 http://dx.doi.org/10.1080/19490976.2022.2044721 |
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