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Host immune response mediates changes in cagA copy number and virulence potential of Helicobacter pylori

Helicobacter pylori is the major risk factor for gastric cancer. H. pylori harboring the type IV secretion system (T4SS) and its effector CagA encoded on the cag pathogenicity Island (cagPAI) increases the risk. H. pylori PMSS1 has a multi-cagA genotype, modulating cagA copy number dynamically from...

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Detalles Bibliográficos
Autores principales: Jang, Sungil, Hansen, Lori M., Su, Hanfu, Solnick, Jay V., Cha, Jeong-Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928821/
https://www.ncbi.nlm.nih.gov/pubmed/35289715
http://dx.doi.org/10.1080/19490976.2022.2044721

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