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Deletion of IP6K1 in mice accelerates tumor growth by dysregulating the tumor-immune microenvironment

A family of inositol hexakisphosphate kinases (IP6Ks) catalyzes the production of inositol pyrophosphate IP(7) (5-diphosphoinositolpentakisphosphate) which is known to modulate various biological events such as cell growth. While targeting IP6K1 in various cancer cells has been well reported to cont...

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Detalles Bibliográficos
Autores principales: Lee, Haein, Park, Seung Ju, Hong, Sehoon, Lim, Seol-Wa, Kim, Seyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928833/
https://www.ncbi.nlm.nih.gov/pubmed/35308129
http://dx.doi.org/10.1080/19768354.2022.2029560