Critical Amino Acid Variants in HLA-DRB1 and -DQB1 Allotypes in the Development of Classical Type 1 Diabetes and Latent Autoimmune Diabetes in Adults in the Japanese Population

The effects of amino acid variants encoded by the human leukocyte antigen (HLA) class II on the development of classical type 1 diabetes (T1D) and latent autoimmune diabetes in adults (LADA) have not been fully elucidated. We retrospectively investigated the HLA-DRB1 and -DQB1 genes of 72 patients w...

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Detalles Bibliográficos
Autores principales: Katahira, Masahito, Tsunekawa, Taku, Mizoguchi, Akira, Yamaguchi, Mariko, Tsuru, Kahori, Takashima, Hiromi, Terada, Ryoma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928954/
https://www.ncbi.nlm.nih.gov/pubmed/34065159
http://dx.doi.org/10.3390/cimb43010009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928954/
https://www.ncbi.nlm.nih.gov/pubmed/34065159
http://dx.doi.org/10.3390/cimb43010009

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