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Critical Amino Acid Variants in HLA-DRB1 and -DQB1 Allotypes in the Development of Classical Type 1 Diabetes and Latent Autoimmune Diabetes in Adults in the Japanese Population
The effects of amino acid variants encoded by the human leukocyte antigen (HLA) class II on the development of classical type 1 diabetes (T1D) and latent autoimmune diabetes in adults (LADA) have not been fully elucidated. We retrospectively investigated the HLA-DRB1 and -DQB1 genes of 72 patients w...
Autores principales: | Katahira, Masahito, Tsunekawa, Taku, Mizoguchi, Akira, Yamaguchi, Mariko, Tsuru, Kahori, Takashima, Hiromi, Terada, Ryoma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928954/ https://www.ncbi.nlm.nih.gov/pubmed/34065159 http://dx.doi.org/10.3390/cimb43010009 |
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