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Losartan Attenuates Insulin Resistance and Regulates Browning Phenomenon of White Adipose Tissue in ob/ob Mice

Insulin resistance (IR) is a villain role to the pathology of fatty liver diseases implicated in adipose tissue dysfunction, which is characterized by lipid droplets (LDs) accumulation and hypoxia-inducible factor 1α (HIF1α) related macrophage infiltration. HIF1α is required for its lipogenic action...

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Detalles Bibliográficos
Autores principales: Liu, Hsuan-Miao, Wang, Cheng-Hui, Chang, Zi-Yu, Huang, Tse-Hung, Lee, Tzung-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929071/
https://www.ncbi.nlm.nih.gov/pubmed/34889901
http://dx.doi.org/10.3390/cimb43030128