Homozygosity Haplotype and Whole-Exome Sequencing Analysis to Identify Potentially Functional Rare Variants Involved in Multiple Sclerosis among Sardinian Families

Multiple Sclerosis (MS) is a complex multifactorial autoimmune disease, whose sex- and age-adjusted prevalence in Sardinia (Italy) is among the highest worldwide. To date, 233 loci were associated with MS and almost 20% of risk heritability is attributable to common genetic variants, but many low-fr...

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Detalles Bibliográficos
Autores principales: Fazia, Teresa, Marzanati, Daria, Carotenuto, Anna Laura, Beecham, Ashley, Hadjixenofontos, Athena, McCauley, Jacob L., Saddi, Valeria, Piras, Marialuisa, Bernardinelli, Luisa, Gentilini, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929092/
https://www.ncbi.nlm.nih.gov/pubmed/34889895
http://dx.doi.org/10.3390/cimb43030125

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