Cargando…
Pancreatic Islets Exhibit Dysregulated Adaptation of Insulin Secretion after Chronic Epinephrine Exposure
Chronic adrenergic stimulation is the dominant factor in impairment of the β-cell function. Sustained adrenergic exposure generates dysregulated insulin secretion in fetal sheep. Similar results have been shown in Min6 under the elevated epinephrine condition, but impairments after adrenergic remova...
Autores principales: | Li, Rui, Huang, Huichai, Limesand, Sean W., Chen, Xiaochuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929152/ https://www.ncbi.nlm.nih.gov/pubmed/34071501 http://dx.doi.org/10.3390/cimb43010020 |
Ejemplares similares
-
Chronic glucolipotoxic conditions in pancreatic islets impair insulin secretion due to dysregulated calcium dynamics, glucose responsiveness and mitochondrial activity
por: Somesh, Baggavalli P, et al.
Publicado: (2013) -
Offspring of Obese Dams Exhibit Sex-Differences in Pancreatic Heparan Sulfate Glycosaminoglycans and Islet Insulin Secretion
por: Casasnovas, Jose, et al.
Publicado: (2021) -
The effect of unhealthy β-cells on insulin secretion in pancreatic islets
por: Pu, Yang, et al.
Publicado: (2013) -
Control of Insulin Secretion by Cholinergic Signaling in the Human Pancreatic Islet
por: Molina, Judith, et al.
Publicado: (2014) -
Respiratory Parameters for the Classification of Dysfunctional Insulin Secretion by Pancreatic Islets
por: Kabra, Uma D., et al.
Publicado: (2021)