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The application of sudoscan for screening microvascular complications in patients with type 2 diabetes
The aim of the study was to evaluate the performance of sudoscan in screening diabetic microvascular complications in patients with type 2 diabete mellitus (T2DM). 515 patients with T2DM aged from 23 to 89 years were included for analysis in our study. The mean age was 60.00 ± 11.37 years and the me...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929165/ https://www.ncbi.nlm.nih.gov/pubmed/35310156 http://dx.doi.org/10.7717/peerj.13089 |
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author | Lin, Kun Wu, Yixi Liu, Shuo Huang, Jiaqi Chen, Guishan Zeng, Qiong |
author_facet | Lin, Kun Wu, Yixi Liu, Shuo Huang, Jiaqi Chen, Guishan Zeng, Qiong |
author_sort | Lin, Kun |
collection | PubMed |
description | The aim of the study was to evaluate the performance of sudoscan in screening diabetic microvascular complications in patients with type 2 diabete mellitus (T2DM). 515 patients with T2DM aged from 23 to 89 years were included for analysis in our study. The mean age was 60.00 ± 11.37 years and the mean duration of T2DM was 8.44 ± 7.56 years. Electrochemical skin conductance (ESC) in hands and feet was evaluated by SUDOCAN. Diabetic peripheral neuropathy (DPN) was diagnosed in 378 patients (44.3%), diabetic kidney disease (DKD) in 161 patients (31.26%), diabetic retinopathy (DR) in 148 patients (28.74%). Hands and feet ESC was significantly and independently associated with the presence of DPN, DKD and DR. Patients with a lower ESC (<60 µS) had 5.63-fold increased likelihood of having DPN, 4.90-fold increased likelihood of having DKD, 1.01-fold increased likelihood of having DR, than those with a higher ESC. Age, duration of T2DM, smoking, renal function and vibration perception thresholds were negatively correlated with ESC. Sudoscan parameters were correlated with diabetic microvascular complications, especially with DPN. Sudoscan could be an effective screening tool in primary health care for early screening microvascular complications. |
format | Online Article Text |
id | pubmed-8929165 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | PeerJ Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-89291652022-03-18 The application of sudoscan for screening microvascular complications in patients with type 2 diabetes Lin, Kun Wu, Yixi Liu, Shuo Huang, Jiaqi Chen, Guishan Zeng, Qiong PeerJ Diabetes and Endocrinology The aim of the study was to evaluate the performance of sudoscan in screening diabetic microvascular complications in patients with type 2 diabete mellitus (T2DM). 515 patients with T2DM aged from 23 to 89 years were included for analysis in our study. The mean age was 60.00 ± 11.37 years and the mean duration of T2DM was 8.44 ± 7.56 years. Electrochemical skin conductance (ESC) in hands and feet was evaluated by SUDOCAN. Diabetic peripheral neuropathy (DPN) was diagnosed in 378 patients (44.3%), diabetic kidney disease (DKD) in 161 patients (31.26%), diabetic retinopathy (DR) in 148 patients (28.74%). Hands and feet ESC was significantly and independently associated with the presence of DPN, DKD and DR. Patients with a lower ESC (<60 µS) had 5.63-fold increased likelihood of having DPN, 4.90-fold increased likelihood of having DKD, 1.01-fold increased likelihood of having DR, than those with a higher ESC. Age, duration of T2DM, smoking, renal function and vibration perception thresholds were negatively correlated with ESC. Sudoscan parameters were correlated with diabetic microvascular complications, especially with DPN. Sudoscan could be an effective screening tool in primary health care for early screening microvascular complications. PeerJ Inc. 2022-03-14 /pmc/articles/PMC8929165/ /pubmed/35310156 http://dx.doi.org/10.7717/peerj.13089 Text en ©2022 Lin et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. |
spellingShingle | Diabetes and Endocrinology Lin, Kun Wu, Yixi Liu, Shuo Huang, Jiaqi Chen, Guishan Zeng, Qiong The application of sudoscan for screening microvascular complications in patients with type 2 diabetes |
title | The application of sudoscan for screening microvascular complications in patients with type 2 diabetes |
title_full | The application of sudoscan for screening microvascular complications in patients with type 2 diabetes |
title_fullStr | The application of sudoscan for screening microvascular complications in patients with type 2 diabetes |
title_full_unstemmed | The application of sudoscan for screening microvascular complications in patients with type 2 diabetes |
title_short | The application of sudoscan for screening microvascular complications in patients with type 2 diabetes |
title_sort | application of sudoscan for screening microvascular complications in patients with type 2 diabetes |
topic | Diabetes and Endocrinology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929165/ https://www.ncbi.nlm.nih.gov/pubmed/35310156 http://dx.doi.org/10.7717/peerj.13089 |
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