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The application of sudoscan for screening microvascular complications in patients with type 2 diabetes

The aim of the study was to evaluate the performance of sudoscan in screening diabetic microvascular complications in patients with type 2 diabete mellitus (T2DM). 515 patients with T2DM aged from 23 to 89 years were included for analysis in our study. The mean age was 60.00 ± 11.37 years and the me...

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Autores principales: Lin, Kun, Wu, Yixi, Liu, Shuo, Huang, Jiaqi, Chen, Guishan, Zeng, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929165/
https://www.ncbi.nlm.nih.gov/pubmed/35310156
http://dx.doi.org/10.7717/peerj.13089
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author Lin, Kun
Wu, Yixi
Liu, Shuo
Huang, Jiaqi
Chen, Guishan
Zeng, Qiong
author_facet Lin, Kun
Wu, Yixi
Liu, Shuo
Huang, Jiaqi
Chen, Guishan
Zeng, Qiong
author_sort Lin, Kun
collection PubMed
description The aim of the study was to evaluate the performance of sudoscan in screening diabetic microvascular complications in patients with type 2 diabete mellitus (T2DM). 515 patients with T2DM aged from 23 to 89 years were included for analysis in our study. The mean age was 60.00 ± 11.37 years and the mean duration of T2DM was 8.44 ± 7.56 years. Electrochemical skin conductance (ESC) in hands and feet was evaluated by SUDOCAN. Diabetic peripheral neuropathy (DPN) was diagnosed in 378 patients (44.3%), diabetic kidney disease (DKD) in 161 patients (31.26%), diabetic retinopathy (DR) in 148 patients (28.74%). Hands and feet ESC was significantly and independently associated with the presence of DPN, DKD and DR. Patients with a lower ESC (<60 µS) had 5.63-fold increased likelihood of having DPN, 4.90-fold increased likelihood of having DKD, 1.01-fold increased likelihood of having DR, than those with a higher ESC. Age, duration of T2DM, smoking, renal function and vibration perception thresholds were negatively correlated with ESC. Sudoscan parameters were correlated with diabetic microvascular complications, especially with DPN. Sudoscan could be an effective screening tool in primary health care for early screening microvascular complications.
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spelling pubmed-89291652022-03-18 The application of sudoscan for screening microvascular complications in patients with type 2 diabetes Lin, Kun Wu, Yixi Liu, Shuo Huang, Jiaqi Chen, Guishan Zeng, Qiong PeerJ Diabetes and Endocrinology The aim of the study was to evaluate the performance of sudoscan in screening diabetic microvascular complications in patients with type 2 diabete mellitus (T2DM). 515 patients with T2DM aged from 23 to 89 years were included for analysis in our study. The mean age was 60.00 ± 11.37 years and the mean duration of T2DM was 8.44 ± 7.56 years. Electrochemical skin conductance (ESC) in hands and feet was evaluated by SUDOCAN. Diabetic peripheral neuropathy (DPN) was diagnosed in 378 patients (44.3%), diabetic kidney disease (DKD) in 161 patients (31.26%), diabetic retinopathy (DR) in 148 patients (28.74%). Hands and feet ESC was significantly and independently associated with the presence of DPN, DKD and DR. Patients with a lower ESC (<60 µS) had 5.63-fold increased likelihood of having DPN, 4.90-fold increased likelihood of having DKD, 1.01-fold increased likelihood of having DR, than those with a higher ESC. Age, duration of T2DM, smoking, renal function and vibration perception thresholds were negatively correlated with ESC. Sudoscan parameters were correlated with diabetic microvascular complications, especially with DPN. Sudoscan could be an effective screening tool in primary health care for early screening microvascular complications. PeerJ Inc. 2022-03-14 /pmc/articles/PMC8929165/ /pubmed/35310156 http://dx.doi.org/10.7717/peerj.13089 Text en ©2022 Lin et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Diabetes and Endocrinology
Lin, Kun
Wu, Yixi
Liu, Shuo
Huang, Jiaqi
Chen, Guishan
Zeng, Qiong
The application of sudoscan for screening microvascular complications in patients with type 2 diabetes
title The application of sudoscan for screening microvascular complications in patients with type 2 diabetes
title_full The application of sudoscan for screening microvascular complications in patients with type 2 diabetes
title_fullStr The application of sudoscan for screening microvascular complications in patients with type 2 diabetes
title_full_unstemmed The application of sudoscan for screening microvascular complications in patients with type 2 diabetes
title_short The application of sudoscan for screening microvascular complications in patients with type 2 diabetes
title_sort application of sudoscan for screening microvascular complications in patients with type 2 diabetes
topic Diabetes and Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929165/
https://www.ncbi.nlm.nih.gov/pubmed/35310156
http://dx.doi.org/10.7717/peerj.13089
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