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Immunological barriers to haematopoietic stem cell gene therapy

Cell and gene therapies using haematopoietic stem cells (HSCs) epitomize the transformative potential of regenerative medicine. Recent clinical successes for gene therapies involving autologous HSC transplantation (HSCT) demonstrate the potential of genetic engineering in this stem cell type for cur...

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Detalles Bibliográficos
Autores principales:	Charlesworth, Carsten T., Hsu, Ian, Wilkinson, Adam C., Nakauchi, Hiromitsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929255/ https://www.ncbi.nlm.nih.gov/pubmed/35301483 http://dx.doi.org/10.1038/s41577-022-00698-0

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