Protein arginine methyltransferase 7 modulates neuronal excitability by interacting with Na(V)1.9

Human Na(V)1.9 (hNa(V)1.9), encoded by SCN11A, is preferentially expressed in nociceptors, and its mutations have been linked to pain disorders. Na(V)1.9 could be a promising drug target for pain relief. However, the modulation of Na(V)1.9 activity has remained elusive. Here, we identified a new can...

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Detalles Bibliográficos
Autores principales: Ma, Tingbin, Li, Lulu, Chen, Rui, Yang, Luyao, Sun, Hao, Du, Shiyue, Xu, Xuan, Cao, Zhijian, Zhang, Xianwei, Zhang, Luoying, Shi, Xiaoliu, Liu, Jing Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929296/
https://www.ncbi.nlm.nih.gov/pubmed/34326297
http://dx.doi.org/10.1097/j.pain.0000000000002421

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