The pharmaceutical excipient PEG400 affect the absorption of baicalein in Caco‐2 monolayer model by interacting with UDP‐glucuronosyltransferases and efflux transport proteins

The bioavailability of drugs is often related to intestinal metabolism and transport mechanisms. In previous studies, pharmaceutical excipients were recognized as inert substances in clinical safety evaluations. However, a large number of studies have shown that pharmaceutical excipients regulate th...

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Detalles Bibliográficos
Autores principales: Cao, Siyuan, Zhang, Min, Yuan, Minyan, Yang, Dan, Zhao, Mei, Zhang, Shuo, Wang, Pengjiao, Zhang, Rongping, Gao, Xiuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929329/
https://www.ncbi.nlm.nih.gov/pubmed/35148019
http://dx.doi.org/10.1002/prp2.928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929329/
https://www.ncbi.nlm.nih.gov/pubmed/35148019
http://dx.doi.org/10.1002/prp2.928

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