Cargando…
Selective Androgen Receptor Modulator Induced Hepatotoxicity
Selective androgen receptor modulators (SARMs) have been developed as an alternate to traditional anabolic steroids due to their favorable effects on the bones and muscles without androgenic side effects. They are very popular among athletes and bodybuilders and are available online or over the coun...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929477/ https://www.ncbi.nlm.nih.gov/pubmed/35340496 http://dx.doi.org/10.7759/cureus.22239 |
_version_ | 1784670869654601728 |
---|---|
author | Khan, Sohaib Fackler, Jaclyn Gilani, Asma Murphy, Stephanie Polintan, Lirio |
author_facet | Khan, Sohaib Fackler, Jaclyn Gilani, Asma Murphy, Stephanie Polintan, Lirio |
author_sort | Khan, Sohaib |
collection | PubMed |
description | Selective androgen receptor modulators (SARMs) have been developed as an alternate to traditional anabolic steroids due to their favorable effects on the bones and muscles without androgenic side effects. They are very popular among athletes and bodybuilders and are available online or over the counter. The FDA has warned of their side effects including liver injury. Here we present the case of a 29-year-old patient who presented with jaundice, fatigue, and elevated liver function tests after starting SARM supplements. His symptoms improved and eventually resolved with stopping the supplements. The purpose of this case report is to raise awareness and educate clinicians of the potential side effect of hepatotoxicity of these supplements that can help in its early identification and management. |
format | Online Article Text |
id | pubmed-8929477 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-89294772022-03-24 Selective Androgen Receptor Modulator Induced Hepatotoxicity Khan, Sohaib Fackler, Jaclyn Gilani, Asma Murphy, Stephanie Polintan, Lirio Cureus Internal Medicine Selective androgen receptor modulators (SARMs) have been developed as an alternate to traditional anabolic steroids due to their favorable effects on the bones and muscles without androgenic side effects. They are very popular among athletes and bodybuilders and are available online or over the counter. The FDA has warned of their side effects including liver injury. Here we present the case of a 29-year-old patient who presented with jaundice, fatigue, and elevated liver function tests after starting SARM supplements. His symptoms improved and eventually resolved with stopping the supplements. The purpose of this case report is to raise awareness and educate clinicians of the potential side effect of hepatotoxicity of these supplements that can help in its early identification and management. Cureus 2022-02-15 /pmc/articles/PMC8929477/ /pubmed/35340496 http://dx.doi.org/10.7759/cureus.22239 Text en Copyright © 2022, Khan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Khan, Sohaib Fackler, Jaclyn Gilani, Asma Murphy, Stephanie Polintan, Lirio Selective Androgen Receptor Modulator Induced Hepatotoxicity |
title | Selective Androgen Receptor Modulator Induced Hepatotoxicity |
title_full | Selective Androgen Receptor Modulator Induced Hepatotoxicity |
title_fullStr | Selective Androgen Receptor Modulator Induced Hepatotoxicity |
title_full_unstemmed | Selective Androgen Receptor Modulator Induced Hepatotoxicity |
title_short | Selective Androgen Receptor Modulator Induced Hepatotoxicity |
title_sort | selective androgen receptor modulator induced hepatotoxicity |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929477/ https://www.ncbi.nlm.nih.gov/pubmed/35340496 http://dx.doi.org/10.7759/cureus.22239 |
work_keys_str_mv | AT khansohaib selectiveandrogenreceptormodulatorinducedhepatotoxicity AT facklerjaclyn selectiveandrogenreceptormodulatorinducedhepatotoxicity AT gilaniasma selectiveandrogenreceptormodulatorinducedhepatotoxicity AT murphystephanie selectiveandrogenreceptormodulatorinducedhepatotoxicity AT polintanlirio selectiveandrogenreceptormodulatorinducedhepatotoxicity |