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Selective Androgen Receptor Modulator Induced Hepatotoxicity

Selective androgen receptor modulators (SARMs) have been developed as an alternate to traditional anabolic steroids due to their favorable effects on the bones and muscles without androgenic side effects. They are very popular among athletes and bodybuilders and are available online or over the coun...

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Autores principales: Khan, Sohaib, Fackler, Jaclyn, Gilani, Asma, Murphy, Stephanie, Polintan, Lirio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929477/
https://www.ncbi.nlm.nih.gov/pubmed/35340496
http://dx.doi.org/10.7759/cureus.22239
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author Khan, Sohaib
Fackler, Jaclyn
Gilani, Asma
Murphy, Stephanie
Polintan, Lirio
author_facet Khan, Sohaib
Fackler, Jaclyn
Gilani, Asma
Murphy, Stephanie
Polintan, Lirio
author_sort Khan, Sohaib
collection PubMed
description Selective androgen receptor modulators (SARMs) have been developed as an alternate to traditional anabolic steroids due to their favorable effects on the bones and muscles without androgenic side effects. They are very popular among athletes and bodybuilders and are available online or over the counter. The FDA has warned of their side effects including liver injury. Here we present the case of a 29-year-old patient who presented with jaundice, fatigue, and elevated liver function tests after starting SARM supplements. His symptoms improved and eventually resolved with stopping the supplements. The purpose of this case report is to raise awareness and educate clinicians of the potential side effect of hepatotoxicity of these supplements that can help in its early identification and management.
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spelling pubmed-89294772022-03-24 Selective Androgen Receptor Modulator Induced Hepatotoxicity Khan, Sohaib Fackler, Jaclyn Gilani, Asma Murphy, Stephanie Polintan, Lirio Cureus Internal Medicine Selective androgen receptor modulators (SARMs) have been developed as an alternate to traditional anabolic steroids due to their favorable effects on the bones and muscles without androgenic side effects. They are very popular among athletes and bodybuilders and are available online or over the counter. The FDA has warned of their side effects including liver injury. Here we present the case of a 29-year-old patient who presented with jaundice, fatigue, and elevated liver function tests after starting SARM supplements. His symptoms improved and eventually resolved with stopping the supplements. The purpose of this case report is to raise awareness and educate clinicians of the potential side effect of hepatotoxicity of these supplements that can help in its early identification and management. Cureus 2022-02-15 /pmc/articles/PMC8929477/ /pubmed/35340496 http://dx.doi.org/10.7759/cureus.22239 Text en Copyright © 2022, Khan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Khan, Sohaib
Fackler, Jaclyn
Gilani, Asma
Murphy, Stephanie
Polintan, Lirio
Selective Androgen Receptor Modulator Induced Hepatotoxicity
title Selective Androgen Receptor Modulator Induced Hepatotoxicity
title_full Selective Androgen Receptor Modulator Induced Hepatotoxicity
title_fullStr Selective Androgen Receptor Modulator Induced Hepatotoxicity
title_full_unstemmed Selective Androgen Receptor Modulator Induced Hepatotoxicity
title_short Selective Androgen Receptor Modulator Induced Hepatotoxicity
title_sort selective androgen receptor modulator induced hepatotoxicity
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929477/
https://www.ncbi.nlm.nih.gov/pubmed/35340496
http://dx.doi.org/10.7759/cureus.22239
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