Performance characteristics of the first Food and Drug Administration (FDA)-cleared digital droplet PCR (ddPCR) assay for BCR::ABL1 monitoring in chronic myelogenous leukemia

Chronic myelogenous leukemia (CML) is a hematopoietic stem cell malignancy that accounts for 15–20% of all cases of leukemia. CML is caused by a translocation between chromosomes 9 and 22 which creates an abnormal fusion gene, BCR::ABL1. The amount of BCR::ABL1 transcript RNA is a marker of disease...

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Detalles Bibliográficos
Autores principales: Shelton, Dawne N., Bhagavatula, Prasanthi, Sepulveda, Nathan, Beppu, Lan, Gandhi, Shital, Qin, Dahui, Hauenstein, Scott, Radich, Jerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929598/
https://www.ncbi.nlm.nih.gov/pubmed/35298544
http://dx.doi.org/10.1371/journal.pone.0265278

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