The glycerol-3-phosphate dehydrogenases GpsA and GlpD constitute the oxidoreductive metabolic linchpin for Lyme disease spirochete host infectivity and persistence in the tick

We have identified GpsA, a predicted glycerol-3-phosphate dehydrogenase, as a virulence factor in the Lyme disease spirochete Borrelia (Borreliella) burgdorferi: GpsA is essential for murine infection and crucial for persistence of the spirochete in the tick. B. burgdorferi has a limited biosyntheti...

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Detalles Bibliográficos
Autores principales: Drecktrah, Dan, Hall, Laura S., Crouse, Bethany, Schwarz, Benjamin, Richards, Crystal, Bohrnsen, Eric, Wulf, Michael, Long, Bonnie, Bailey, Jessica, Gherardini, Frank, Bosio, Catharine M., Lybecker, Meghan C., Samuels, D. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929704/
https://www.ncbi.nlm.nih.gov/pubmed/35255112
http://dx.doi.org/10.1371/journal.ppat.1010385

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