Beclin-1 exerts protective effects against cerebral ischemia-reperfusion injury by promoting DNA damage repair through a non-autophagy-dependent regulatory mechanism

Cerebral ischemia-reperfusion (I/R) can result in severe brain injury, for which there are no optimal treatment options. I/R is often accompanied by increased autophagy. Beclin-1, a central player in autophagy, has been extensively studied in I/R; however, to date, at least to the best of our knowle...

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Autores principales: Luo, Hongcheng, Huang, Deyou, Tang, Xionglin, Liu, Yu, Luo, Qisheng, Liu, Chunhong, Huang, Huatuo, Chen, Wencheng, Qi, Zhongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930093/
https://www.ncbi.nlm.nih.gov/pubmed/35266018
http://dx.doi.org/10.3892/ijmm.2022.5117

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