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A study to predict fracture risk using bone mineral density and FRAX score in patients on chronic maintenance haemodialysis

INTRODUCTION: Disturbances in mineral and bone metabolism are prevalent in chronic kidney disease (CKD) and are important causes of morbidity also their diagnosis often delayed and require a spectrum of investigations. The current study attempts to predict and correlate, the fracture risk using simp...

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Detalles Bibliográficos
Autores principales: Patro, Sunil K., Pawar, Neeraj, Biswas, Diwashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930127/
https://www.ncbi.nlm.nih.gov/pubmed/35309612
http://dx.doi.org/10.4103/jfmpc.jfmpc_901_21
Descripción
Sumario:INTRODUCTION: Disturbances in mineral and bone metabolism are prevalent in chronic kidney disease (CKD) and are important causes of morbidity also their diagnosis often delayed and require a spectrum of investigations. The current study attempts to predict and correlate, the fracture risk using simple tools like BMD and FRAX (Fracture Risk Assessment Tool) score in CKD patients. METHODS: A cross-sectional study among 50 CKD patients age more that 40 years attending OPD (Out Patient Department) at a tertiary care Hospital in north India. RESULTS: There is a negative correlation between BMD (NOF) and FRAX score for hip fracture risk and major osteoporotic fracture risk. CONCLUSION: The 10-year fracture risk in these patients, as predicted by FRAX score using FRAX (Indian) calculator, was significantly higher in CKD patients. RECOMMENDATION: FRAX can be useful tool for early screening of fracture risk in such situations for timely interventions.