Cargando…

Elucidating the Novel Mechanism of Ligustrazine in Preventing Postoperative Peritoneal Adhesion Formation

Postoperative peritoneal adhesion (PPA) is a major clinical complication after open surgery or laparoscopic procedure. Ligustrazine is the active ingredient extracted from the natural herb Ligusticum chuanxiong Hort, which has promising antiadhesion properties. This study is aimed at revealing the u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Lili, Li, Zhengjun, Chen, Yao, Chen, Feiyan, Sun, Haopeng, Zhao, Min, Chen, Yanqi, Wang, Yali, Li, Wenlin, Zeng, Li, Bian, Yaoyao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930249/ https://www.ncbi.nlm.nih.gov/pubmed/35308169 http://dx.doi.org/10.1155/2022/9226022

Ejemplares similares

Effect of ligustrazine nanoparticles on Th1/Th2 balance by TLR4/MyD88/NF-κB pathway in rats with postoperative peritoneal adhesion
por: Yang, Lili, et al.
Publicado: (2021)

Paeoniflorin prevents postoperative peritoneal adhesion formation in an experimental rat model
por: Gao, Qi, et al.
Publicado: (2017)

P-glycoprotein Mediates Postoperative Peritoneal Adhesion Formation by Enhancing Phosphorylation of the Chloride Channel-3
por: Deng, Lulu, et al.
Publicado: (2016)

LincRNA Cox-2 Regulates Lipopolysaccharide-Induced Inflammatory Response of Human Peritoneal Mesothelial Cells via Modulating miR-21/NF-κB Axis
por: Bian, Yaoyao, et al.
Publicado: (2019)

Identification of candidate biomarkers correlated with pathogenesis of postoperative peritoneal adhesion by using microarray analysis
por: Bian, Yao-Yao, et al.
Publicado: (2020)

Identification of Key Genes and Pathways in Post-traumatic Stress Disorder Using Microarray Analysis
por: Bian, Yaoyao, et al.
Publicado: (2019)

Effects of Glycerol and Sodium Pentaborate Formulation on Prevention of Postoperative Peritoneal Adhesion Formation
por: Aysan, Erhan, et al.
Publicado: (2020)

Pharmacokinetic study on the effect of ligustrazine–tangeretin co‐administration on the pharmacokinetics of ligustrazine and its potential mechanism in rats
por: Liu, Dandan, et al.
Publicado: (2023)

Ligustrazine monomer against cerebral ischemia/reperfusion injury
por: Gao, Hai-jun, et al.
Publicado: (2015)

Effect of Ligustrazine on Endometrium Injury of Thin Endometrium Rats
por: Ye, Qing, et al.
Publicado: (2019)

Multifunctional Oxidized Dextran–Metformin as a Tissue‐Adhesive Hydrogel to Prevent Postoperative Peritoneal Adhesions in Patients with Metabolic Syndrome
por: Liu, Xi, et al.
Publicado: (2023)

Ligustrazine inhibits the viability and motility of colon cancer cells
por: Chen, Xiaochao, et al.
Publicado: (2020)

Effect of ligustrazine on preventing contrast-induced nephropathy in patients with unstable angina
por: Ye, Ziliang, et al.
Publicado: (2017)

Effects of ligustrazine on the expression of neurotransmitters in the trigeminal ganglion of a rat migraine model
por: Li, Hui, et al.
Publicado: (2021)

Melt electrowriting-printed peritoneal scaffold prevents peritoneal adhesion and facilitates peritoneal repair
por: Li, Sicheng, et al.
Publicado: (2023)

Efficacy of Ligustrazine Injection as Adjunctive Therapy for Angina Pectoris: A Systematic Review and Meta-Analysis
por: Shao, Huikai, et al.
Publicado: (2015)

Meta-Analysis of Clinical Efficacy and Safety of Ligustrazine in the Treatment of Idiopathic Pulmonary Fibrosis
por: Wu, Xiaozheng, et al.
Publicado: (2020)

Meta-Analysis of Preventive and Therapeutic Effects of Ligustrazine on Airway Remodeling in Asthmatic Rats
por: Hua, Yu-shuang, et al.
Publicado: (2022)

Ligustrazine Inhibits the Migration and Invasion of Renal Cell Carcinoma
por: Zhang, Xufeng, et al.
Publicado: (2023)

Equity and Efficiency of Health Resource Allocation of Chinese Medicine in Mainland China: 2013–2017
por: Li, Zhengjun, et al.
Publicado: (2020)

In vivo expression of thrombospondin-1 suppresses the formation of peritoneal adhesion in rats
por: Tai, Yun-Sheng, et al.
Publicado: (2019)

Severe inflammatory reaction induced by peritoneal trauma is the key driving mechanism of postoperative adhesion formation
por: Pismensky, Sergei V, et al.
Publicado: (2011)

Long intestinal tube splinting prevents postoperative adhesive small-bowel obstruction in sclerosing encapsulating peritonitis
por: Li, Min, et al.
Publicado: (2014)

Effect of Emodin on Preventing Postoperative Intra-Abdominal Adhesion Formation
por: Wei, Guangbing, et al.
Publicado: (2017)

Ligustrazine Prevents Intervertebral Disc Degeneration via Suppression of Aberrant TGFβ Activation in Nucleus Pulposus Cells
por: Liu, Shufen, et al.
Publicado: (2019)

Ligustrazine Inhibits Cartilage Endplate Hypertrophy via Suppression of TGF-β1
por: Liu, Shufen, et al.
Publicado: (2016)

Effect of Intraperitoneal Curcumin Instillation on Postoperative Peritoneal Adhesions
por: Türkoğlu, Ahmet, et al.
Publicado: (2015)

Prevalence of type 2 diabetes mellitus among inland residents in China (2000–2014): A meta‐analysis
por: Yang, Lili, et al.
Publicado: (2016)

Biodegradable and thermosensitive micelles inhibit ischemia-induced postoperative peritoneal adhesion
por: Wu, Qinjie, et al.
Publicado: (2014)

Elucidating the fundamental fibrotic processes driving abdominal adhesion formation
por: Foster, Deshka S., et al.
Publicado: (2020)

Synthesis and Discovery of Ligustrazine–Heterocycle Derivatives as Antitumor Agents
por: Ma, Shitang, et al.
Publicado: (2022)

Protective effect of ligustrazine on oxidative stress and apoptosis following testicular torsion in rats
por: Chen, Songmao, et al.
Publicado: (2023)

Synthesis and Biological Evaluation of New Ligustrazine Derivatives as Anti-Tumor Agents
por: Wang, Penglong, et al.
Publicado: (2012)

Protective Effect of Ligustrazine on Lumbar Intervertebral Disc Degeneration of Rats Induced by Prolonged Upright Posture
por: Liang, Qian-Qian, et al.
Publicado: (2014)

Antithrombotic effect of ligustrazine hydrochloride injection on the model of induced arteriovenous shunt thrombosis
por: Wang, Peng, et al.
Publicado: (2013)

Amino Acid Derivatives of Ligustrazine-Oleanolic Acid as New Cytotoxic Agents
por: Chu, Fuhao, et al.
Publicado: (2014)

Ligustrazine Inhibits Lung Phosphodiesterase Activity in a Rat Model of Allergic Asthma
por: Wang, Yajuan, et al.
Publicado: (2022)

Effect of platelet-rich plasma on postoperative peritoneal inflammation and adhesions
por: Karakaş, Dursun Özgür, et al.
Publicado: (2020)

Berberine prevents primary peritoneal adhesion and adhesion reformation by directly inhibiting TIMP-1
por: Liu, Xin, et al.
Publicado: (2020)

Efficacy and mechanism of tanshinone IIA liquid nanoparticles in preventing experimental postoperative peritoneal adhesions in vivo and in vitro
por: Qin, Fei, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8bkgpm0oi3gincvjsfa8ia94nb