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Highly-multiplexed volumetric mapping with Raman dye imaging and tissue clearing

Mapping the localization of multiple proteins in their native 3D context would be useful across many areas of biomedicine, but multiplexed fluorescence imaging has limited intrinsic multiplexing capability, and most methods for increasing multiplexing can only be applied to thin samples (<100 μm)...

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Detalles Bibliográficos
Autores principales: Shi, Lixue, Wei, Mian, Miao, Yupeng, Qian, Naixin, Shi, Lingyan, Singer, Ruth A., Benninger, Richard K. P., Min, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930416/
https://www.ncbi.nlm.nih.gov/pubmed/34608326
http://dx.doi.org/10.1038/s41587-021-01041-z