Cargando…
Direct targeting of amplified gene loci for pro-apoptotic anticancer therapy
Gene amplification drives oncogenesis in a broad spectrum of cancers. A number of drugs have been developed to inhibit the protein products of amplified driver genes, but their clinical efficacy is often hampered by drug resistance. Here, we introduce a therapeutic strategy for targeting cancer-asso...
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930417/ https://www.ncbi.nlm.nih.gov/pubmed/34711990 http://dx.doi.org/10.1038/s41587-021-01057-5 |