Targeting LRRC15 Inhibits Metastatic Dissemination of Ovarian Cancer

Dissemination of ovarian cancer cells can lead to inoperable metastatic lesions in the bowel and omentum that cause patient death. Here we show that LRRC15, a type-I 15-leucine–rich repeat-containing membrane protein, highly overexpressed in ovarian cancer bowel metastases compared with matched prim...

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Detalles Bibliográficos
Autores principales: Ray, Upasana, Jung, Deok-Beom, Jin, Ling, Xiao, Yinan, Dasari, Subramanyam, Sarkar Bhattacharya, Sayantani, Thirusangu, Prabhu, Staub, Julie K., Roy, Debarshi, Roy, Bhaskar, Weroha, S. John, Hou, Xiaonan, Purcell, James W., Bakkum-Gamez, Jamie N., Kaufmann, Scott H., Kannan, Nagarajan, Mitra, Anirban K., Shridhar, Viji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Molecular Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930558/
https://www.ncbi.nlm.nih.gov/pubmed/34654724
http://dx.doi.org/10.1158/0008-5472.CAN-21-0622

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