T cell responses to SARS-CoV-2 spike cross-recognize Omicron

The SARS-CoV-2 Omicron variant (B.1.1.529) has multiple spike protein mutations(1,2) that contribute to viral escape from antibody neutralization(3–6) and reduce vaccine protection from infection(7,8). The extent to which other components of the adaptive response such as T cells may still target Omi...

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Detalles Bibliográficos
Autores principales: Keeton, Roanne, Tincho, Marius B., Ngomti, Amkele, Baguma, Richard, Benede, Ntombi, Suzuki, Akiko, Khan, Khadija, Cele, Sandile, Bernstein, Mallory, Karim, Farina, Madzorera, Sharon V., Moyo-Gwete, Thandeka, Mennen, Mathilda, Skelem, Sango, Adriaanse, Marguerite, Mutithu, Daniel, Aremu, Olukayode, Stek, Cari, du Bruyn, Elsa, Van Der Mescht, Mieke A., de Beer, Zelda, de Villiers, Talita R., Bodenstein, Annie, van den Berg, Gretha, Mendes, Adriano, Strydom, Amy, Venter, Marietjie, Giandhari, Jennifer, Naidoo, Yeshnee, Pillay, Sureshnee, Tegally, Houriiyah, Grifoni, Alba, Weiskopf, Daniela, Sette, Alessandro, Wilkinson, Robert J., de Oliveira, Tulio, Bekker, Linda-Gail, Gray, Glenda, Ueckermann, Veronica, Rossouw, Theresa, Boswell, Michael T., Bhiman, Jinal N., Moore, Penny L., Sigal, Alex, Ntusi, Ntobeko A. B., Burgers, Wendy A., Riou, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930768/
https://www.ncbi.nlm.nih.gov/pubmed/35102311
http://dx.doi.org/10.1038/s41586-022-04460-3

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