Cargando…
Structural basis of phosphatidylinositol 3-kinase C2α function
Phosphatidylinositol 3-kinase type 2α (PI3KC2α) is an essential member of the structurally unresolved class II PI3K family with crucial functions in lipid signaling, endocytosis, angiogenesis, viral replication, platelet formation and a role in mitosis. The molecular basis of these activities of PI3...
Autores principales: | Lo, Wen-Ting, Zhang, Yingyi, Vadas, Oscar, Roske, Yvette, Gulluni, Federico, De Santis, Maria Chiara, Zagar, Andreja Vujicic, Stephanowitz, Heike, Hirsch, Emilio, Liu, Fan, Daumke, Oliver, Kudryashev, Misha, Haucke, Volker |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930771/ https://www.ncbi.nlm.nih.gov/pubmed/35256802 http://dx.doi.org/10.1038/s41594-022-00730-w |
Ejemplares similares
-
Development of selective inhibitors of phosphatidylinositol 3-kinase C2α
por: Lo, Wen-Ting, et al.
Publicado: (2022) -
PI(3,4)P2 Signaling in Cancer and Metabolism
por: Gozzelino, Luca, et al.
Publicado: (2020) -
A phosphatidylinositol (4,5)-bisphosphate binding site within μ2-adaptin regulates clathrin-mediated endocytosis
por: Rohde, Gundula, et al.
Publicado: (2002) -
Targeting PI3K in Cancer: Any Good News?
por: Martini, Miriam, et al.
Publicado: (2013) -
Targeting PI3K/AKT/mTOR Signaling Pathway in Breast Cancer
por: Li, Huayi, et al.
Publicado: (2021)