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Intratumoral administration of the antisecretory peptide AF16 cures murine gliomas and modulates macrophage functions

Glioblastoma has remained the deadliest primary brain tumor while its current therapy offers only modest survival prolongation. Immunotherapy has failed to record notable benefits in routine glioblastoma treatment. Conventionally, immunotherapy relies on T cells as tumor-killing agents; however, T c...

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Detalles Bibliográficos
Autores principales: Kopecky, Jan, Pérez, Julio Enríquez, Eriksson, Håkan, Visse, Edward, Siesjö, Peter, Darabi, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930985/
https://www.ncbi.nlm.nih.gov/pubmed/35301393
http://dx.doi.org/10.1038/s41598-022-08618-x

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