The RNA-binding protein Musashi2 governs osteoblast-adipocyte lineage commitment by suppressing PPARγ signaling

Osteoporosis caused by aging is characterized by reduced bone mass and accumulated adipocytes in the bone marrow cavity. How the balance between osteoblastogenesis and adipogenesis from bone marrow mesenchymal stem cells (BMSCs) is lost upon aging is still unclear. Here, we found that the RNA-bindin...

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Detalles Bibliográficos
Autores principales: Suo, Jinlong, Zou, Sihai, Wang, Jinghui, Han, Yujiao, Zhang, Lingli, Lv, Chenchen, Jiang, Bo, Ren, Qian, Chen, Long, Yang, Lele, Ji, Ping, Zheng, Xianyou, Hu, Ping, Zou, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930990/
https://www.ncbi.nlm.nih.gov/pubmed/35301280
http://dx.doi.org/10.1038/s41413-022-00202-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930990/
https://www.ncbi.nlm.nih.gov/pubmed/35301280
http://dx.doi.org/10.1038/s41413-022-00202-3

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