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Skp2 stabilizes Mcl-1 and confers radioresistance in colorectal cancer

Overexpression of Skp2 plays a critical role in tumorigenesis and correlates with poor prognosis in human malignancies. Thus, Skp2 has been proposed as an attractive target for anti-tumor interventions. The expression of Skp2 in human colorectal cancer (CRC) and the role of Skp2 in tumorigenic prope...

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Detalles Bibliográficos
Autores principales:	Yu, Xinfang, Zhou, Li, Liu, Wenbin, Liu, Lijun, Gao, Feng, Li, Wei, Liu, Haidan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930992/ https://www.ncbi.nlm.nih.gov/pubmed/35301297 http://dx.doi.org/10.1038/s41419-022-04685-0

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