Cargando…

Fully automated platelet differential interference contrast image analysis via deep learning

Platelets mediate arterial thrombosis, a leading cause of myocardial infarction and stroke. During injury, platelets adhere and spread over exposed subendothelial matrix substrates of the damaged blood vessel wall. The mechanisms which govern platelet activation and their interaction with a range of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kempster, Carly, Butler, George, Kuznecova, Elina, Taylor, Kirk A., Kriek, Neline, Little, Gemma, Sowa, Marcin A., Sage, Tanya, Johnson, Louise J., Gibbins, Jonathan M., Pollitt, Alice Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931011/ https://www.ncbi.nlm.nih.gov/pubmed/35301400 http://dx.doi.org/10.1038/s41598-022-08613-2

Ejemplares similares

Protein Disulphide Isomerase and NADPH Oxidase 1 Cooperate to Control Platelet Function and Are Associated with Cardiometabolic Disease Risk Factors
por: Gaspar, Renato Simões, et al.
Publicado: (2021)

Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction
por: Unsworth, Amanda J., et al.
Publicado: (2018)

Multiparameter phenotyping of platelet reactivity for stratification of human cohorts
por: Dunster, Joanne L., et al.
Publicado: (2021)

Cucurbitacins Elicit Anti-Platelet Activity via Perturbation of the Cytoskeleton and Integrin Function
por: Kriek, Neline, et al.
Publicado: (2022)

Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability
por: Mitchell, Joanne L., et al.
Publicado: (2023)

Pirtobrutinib results in reversible platelet dysfunction compared to ibrutinib and acalabrutinib
por: Bye, Alexander P., et al.
Publicado: (2022)

RXR Ligands Negatively Regulate Thrombosis and Hemostasis
por: Unsworth, Amanda J., et al.
Publicado: (2017)

Farnesoid X Receptor and Liver X Receptor Ligands Initiate Formation of Coated Platelets
por: Unsworth, Amanda J., et al.
Publicado: (2017)

Mind the gap: connexins and pannexins in platelet function
por: Taylor, Kirk a, et al.
Publicado: (2021)

Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets
por: Bye, Alexander P., et al.
Publicado: (2021)

Characterisation of Platelet Sensitivity in Severe COVID-19
por: Saputil, Rocel C., et al.
Publicado: (2022)

Flow cytometry for near-patient testing in premature neonates reveals variation in platelet function: a novel approach to guide platelet transfusion
por: Waller, Amie K., et al.
Publicado: (2019)

PPARγ agonists negatively regulate αIIbβ3 integrin outside‐in signaling and platelet function through up‐regulation of protein kinase A activity
por: Unsworth, A. J., et al.
Publicado: (2017)

G protein–coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1
por: Downes, Kate, et al.
Publicado: (2022)

Antiplatelet properties of Pim kinase inhibition are mediated through disruption of thromboxane A2 receptor signaling
por: Unsworth, Amanda J., et al.
Publicado: (2020)

Staphylococcus aureus Lipoteichoic Acid Inhibits Platelet Activation and Thrombus Formation via the Paf Receptor
por: Waller, Amie K., et al.
Publicado: (2013)

The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and hemostasis
por: Sasikumar, P., et al.
Publicado: (2018)

Connexin40 regulates platelet function
por: Vaiyapuri, Sakthivel, et al.
Publicado: (2013)

Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation
por: Dunster, Joanne L., et al.
Publicado: (2019)

Peripheral tachykinins and the neurokinin receptor NK1 are required for platelet thrombus formation
por: Jones, Sarah, et al.
Publicado: (2008)

Platelet-Derived Inhibitors of Platelet Activation
por: Unsworth, A. J., et al.
Publicado: (2017)

A dual role for integrin-linked kinase in platelets: regulating integrin function and α-granule secretion
por: Tucker, Katherine L., et al.
Publicado: (2008)

Role of heat shock protein 47 in platelet glycoprotein VI dimerization and signaling
por: AlOuda, Sarah K., et al.
Publicado: (2023)

Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring
por: Gaspar, Renato S., et al.
Publicado: (2021)

Automated Contouring of Contrast and Noncontrast Computed Tomography Liver Images With Fully Convolutional Networks
por: Anderson, Brian M., et al.
Publicado: (2020)

Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis
por: Flora, Gagan D., et al.
Publicado: (2019)

Non-genomic effects of PPARγ ligands: inhibition of GPVI-stimulated platelet activation
por: Moraes, L A, et al.
Publicado: (2010)

Fully Automated Support System for Diagnosis of Breast Cancer in Contrast-Enhanced Spectral Mammography Images
por: Fanizzi, Annarita, et al.
Publicado: (2019)

Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells
por: Moraes, L A, et al.
Publicado: (2010)

Fully-automated deep learning-based flow quantification of 2D CINE phase contrast MRI
por: Pradella, Maurice, et al.
Publicado: (2022)

Interference of medical contrast media on laboratory testing
por: Lippi, Giuseppe, et al.
Publicado: (2014)

Analytical Interference by Contrast Agents in Biochemical Assays
por: Otnes, Sigrid, et al.
Publicado: (2017)

Near Field Differential Interference Contrast Microscopy
por: Heydarian, Hesam, et al.
Publicado: (2020)

Delineating Zinc Influx Mechanisms during Platelet Activation
por: Kuravi, Sahithi J., et al.
Publicado: (2023)

Katacine Is a New Ligand of CLEC-2 that Acts as a Platelet Agonist
por: Morán, Luis A., et al.
Publicado: (2022)

Anticoagulants Interfere With the Angiogenic and Regenerative Responses Mediated by Platelets
por: Oneto, Paula, et al.
Publicado: (2020)

Fully integrated, fully automated generation of short tandem repeat profiles
por: Tan, Eugene, et al.
Publicado: (2013)

Detection of Retinitis Pigmentosa by Differential Interference Contrast Microscopy
por: Oh, Juyeong, et al.
Publicado: (2014)

Single-shot isotropic differential interference contrast microscopy
por: Wang, Xinwei, et al.
Publicado: (2023)

The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function
por: Holbrook, L-M, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_69ianhqobn0nmji7d9q0fd034s