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Cytogenetic abnormalities in essential thrombocythemia: Clinical and molecular correlates and prognostic relevance in 809 informative cases

Cytogenetic studies among 809 consecutive patients with essential thrombocythemia (ET; median age 59 years; 65% females) revealed normal karyotype in 754 (93%), loss of chromosome Y only (-Y) in 16 (2%), and abnormalities other than -Y in 39 (4.8%), the most frequent being sole 20q- (n = 8). At pres...

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Detalles Bibliográficos
Autores principales:	Gangat, Naseema, Jadoon, Yamna, Szuber, Natasha, Hanson, Curtis A., Wolanskyj-Spinner, Alexandra P., Ketterling, Rhett P., Pardanani, Animesh, Tefferi, Ayalew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931050/ https://www.ncbi.nlm.nih.gov/pubmed/35301278 http://dx.doi.org/10.1038/s41408-022-00639-z

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