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Structure-guided unlocking of Na(X) reveals a non-selective tetrodotoxin-sensitive cation channel

Unlike classical voltage-gated sodium (Na(V)) channels, Na(X) has been characterized as a voltage-insensitive, tetrodotoxin-resistant, sodium (Na(+))-activated channel involved in regulating Na(+) homeostasis. However, Na(X) remains refractory to functional characterization in traditional heterologo...

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Detalles Bibliográficos
Autores principales:	Noland, Cameron L., Chua, Han Chow, Kschonsak, Marc, Heusser, Stephanie Andrea, Braun, Nina, Chang, Timothy, Tam, Christine, Tang, Jia, Arthur, Christopher P., Ciferri, Claudio, Pless, Stephan Alexander, Payandeh, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931054/ https://www.ncbi.nlm.nih.gov/pubmed/35301303 http://dx.doi.org/10.1038/s41467-022-28984-4

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