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Single-molecule imaging of microRNA-mediated gene silencing in cells

MicroRNAs (miRNAs) are small non-coding RNAs, which regulate the expression of thousands of genes; miRNAs silence gene expression from complementary mRNAs through translational repression and mRNA decay. For decades, the function of miRNAs has been studied primarily by ensemble methods, where a bulk...

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Detalles Bibliográficos
Autores principales: Kobayashi, Hotaka, Singer, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931058/
https://www.ncbi.nlm.nih.gov/pubmed/35301300
http://dx.doi.org/10.1038/s41467-022-29046-5