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The Oligodendrocyte Transcription Factor 2 OLIG2 regulates transcriptional repression during myelinogenesis in rodents
OLIG2 is a transcription factor that activates the expression of myelin-associated genes in the oligodendrocyte-lineage cells. However, the mechanisms of myelin gene inactivation are unclear. Here, we uncover a non-canonical function of OLIG2 in transcriptional repression to modulate myelinogenesis...
Autores principales: | Zhang, Kunkun, Chen, Shaoxuan, Yang, Qihua, Guo, Shuanghui, Chen, Qiang, Liu, Zhixiong, Li, Li, Jiang, Mengyun, Li, Hongda, Hu, Jin, Pan, Xu, Deng, Wenbo, Xiao, Naian, Wang, Bo, Wang, Zhan-xiang, Zhang, Liang, Mo, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931116/ https://www.ncbi.nlm.nih.gov/pubmed/35301318 http://dx.doi.org/10.1038/s41467-022-29068-z |
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