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The Oligodendrocyte Transcription Factor 2 OLIG2 regulates transcriptional repression during myelinogenesis in rodents

OLIG2 is a transcription factor that activates the expression of myelin-associated genes in the oligodendrocyte-lineage cells. However, the mechanisms of myelin gene inactivation are unclear. Here, we uncover a non-canonical function of OLIG2 in transcriptional repression to modulate myelinogenesis...

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Detalles Bibliográficos
Autores principales: Zhang, Kunkun, Chen, Shaoxuan, Yang, Qihua, Guo, Shuanghui, Chen, Qiang, Liu, Zhixiong, Li, Li, Jiang, Mengyun, Li, Hongda, Hu, Jin, Pan, Xu, Deng, Wenbo, Xiao, Naian, Wang, Bo, Wang, Zhan-xiang, Zhang, Liang, Mo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931116/
https://www.ncbi.nlm.nih.gov/pubmed/35301318
http://dx.doi.org/10.1038/s41467-022-29068-z

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