Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate

Hepatitis C virus (HCV) is a global disease burden, and a preventive vaccine is needed to control or eradicate the virus. Despite the advent of effective antiviral therapy, this treatment is not accessible to many patients and does not prevent reinfection, making chronic hepatitis C an ongoing globa...

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Detalles Bibliográficos
Autores principales: Wang, Ruixue, Suzuki, Saori, Guest, Johnathan D., Heller, Brigitte, Almeda, Maricar, Andrianov, Alexander K., Marin, Alexander, Mariuzza, Roy A., Keck, Zhen-Yong, Foung, Steven K. H., Yunus, Abdul S., Pierce, Brian G., Toth, Eric A., Ploss, Alexander, Fuerst, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931252/
https://www.ncbi.nlm.nih.gov/pubmed/35263223
http://dx.doi.org/10.1073/pnas.2112008119

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