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Engineered nanoparticles enable deep proteomics studies at scale by leveraging tunable nano–bio interactions

Deep interrogation of plasma proteins on a large scale is a challenge due to the number and concentration of proteins, which span a dynamic range of over 10 orders of magnitude. Current plasma proteomics workflows employ labor-intensive protocols combining abundant protein depletion and sample fract...

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Detalles Bibliográficos
Autores principales: Ferdosi, Shadi, Tangeysh, Behzad, Brown, Tristan R., Everley, Patrick A., Figa, Michael, McLean, Matthew, Elgierari, Eltaher M., Zhao, Xiaoyan, Garcia, Veder J., Wang, Tianyu, Chang, Matthew E. K., Riedesel, Kateryna, Chu, Jessica, Mahoney, Max, Xia, Hongwei, O’Brien, Evan S., Stolarczyk, Craig, Harris, Damian, Platt, Theodore L., Ma, Philip, Goldberg, Martin, Langer, Robert, Flory, Mark R., Benz, Ryan, Tao, Wei, Cuevas, Juan Cruz, Batzoglou, Serafim, Blume, John E., Siddiqui, Asim, Hornburg, Daniel, Farokhzad, Omid C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931255/
https://www.ncbi.nlm.nih.gov/pubmed/35275789
http://dx.doi.org/10.1073/pnas.2106053119