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Stem cell induced inflammatory hypertrophy of the cauda equina

Stem cell therapy can present clinicians with challenging clinical scenarios, as access to such treatments outpaces the research into their efficacy and safety due to the burgeoning trend of international travel to acquire stem cell therapy, or “stem cell tourism.” Treatment of neurologic conditions...

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Detalles Bibliográficos
Autores principales: Brumbaugh, Aaron D., Podolsky, Alan, Kulzer, Matthew H., Spearman, Michael P., Goldberg, Michael F., Chang, Warren M., Khatoon, Nazia, Dantey, Kossivi, Li, Charles Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931292/
https://www.ncbi.nlm.nih.gov/pubmed/35309384
http://dx.doi.org/10.1016/j.radcr.2022.02.021
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author Brumbaugh, Aaron D.
Podolsky, Alan
Kulzer, Matthew H.
Spearman, Michael P.
Goldberg, Michael F.
Chang, Warren M.
Khatoon, Nazia
Dantey, Kossivi
Li, Charles Q.
author_facet Brumbaugh, Aaron D.
Podolsky, Alan
Kulzer, Matthew H.
Spearman, Michael P.
Goldberg, Michael F.
Chang, Warren M.
Khatoon, Nazia
Dantey, Kossivi
Li, Charles Q.
author_sort Brumbaugh, Aaron D.
collection PubMed
description Stem cell therapy can present clinicians with challenging clinical scenarios, as access to such treatments outpaces the research into their efficacy and safety due to the burgeoning trend of international travel to acquire stem cell therapy, or “stem cell tourism.” Treatment of neurologic conditions remains an enticing potential application of stem cell therapy, often administered intrathecally. In response to such therapy, multiple adverse events have been described in the literature, including neoplasms, demyelinating disease, and seizures, among others. We present a case of symptomatic inflammatory cauda equina nerve root hypertrophy due to intrathecal stem cell infusion, representing a rare but significant complication.
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spelling pubmed-89312922022-03-19 Stem cell induced inflammatory hypertrophy of the cauda equina Brumbaugh, Aaron D. Podolsky, Alan Kulzer, Matthew H. Spearman, Michael P. Goldberg, Michael F. Chang, Warren M. Khatoon, Nazia Dantey, Kossivi Li, Charles Q. Radiol Case Rep Case Report Stem cell therapy can present clinicians with challenging clinical scenarios, as access to such treatments outpaces the research into their efficacy and safety due to the burgeoning trend of international travel to acquire stem cell therapy, or “stem cell tourism.” Treatment of neurologic conditions remains an enticing potential application of stem cell therapy, often administered intrathecally. In response to such therapy, multiple adverse events have been described in the literature, including neoplasms, demyelinating disease, and seizures, among others. We present a case of symptomatic inflammatory cauda equina nerve root hypertrophy due to intrathecal stem cell infusion, representing a rare but significant complication. Elsevier 2022-03-15 /pmc/articles/PMC8931292/ /pubmed/35309384 http://dx.doi.org/10.1016/j.radcr.2022.02.021 Text en © 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Brumbaugh, Aaron D.
Podolsky, Alan
Kulzer, Matthew H.
Spearman, Michael P.
Goldberg, Michael F.
Chang, Warren M.
Khatoon, Nazia
Dantey, Kossivi
Li, Charles Q.
Stem cell induced inflammatory hypertrophy of the cauda equina
title Stem cell induced inflammatory hypertrophy of the cauda equina
title_full Stem cell induced inflammatory hypertrophy of the cauda equina
title_fullStr Stem cell induced inflammatory hypertrophy of the cauda equina
title_full_unstemmed Stem cell induced inflammatory hypertrophy of the cauda equina
title_short Stem cell induced inflammatory hypertrophy of the cauda equina
title_sort stem cell induced inflammatory hypertrophy of the cauda equina
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931292/
https://www.ncbi.nlm.nih.gov/pubmed/35309384
http://dx.doi.org/10.1016/j.radcr.2022.02.021
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