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Tsc2 knockout counteracts ubiquitin-proteasome system insufficiency and delays photoreceptor loss in retinitis pigmentosa
Methods to stimulate protein degradation through the ubiquitin-proteasome system (UPS) are being investigated as approaches to treat multiple human diseases and delay aging. Recent studies highlighted a nontrivial relationship between the mammalian target of rapamycin complex 1 (mTORC1) pathway and...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931319/ https://www.ncbi.nlm.nih.gov/pubmed/35275792 http://dx.doi.org/10.1073/pnas.2118479119 |