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Reactive Oxygen Species-Responsive Nanococktail With Self-Amplificated Drug Release for Efficient Co-Delivery of Paclitaxel/Cucurbitacin B and Synergistic Treatment of Gastric Cancer

Application of drug combinations is a powerful strategy for the therapy of advanced gastric cancer. However, the clinical use of such combinations is greatly limited by the occurrence of severe systemic toxicity. Although polymeric-prodrug-based nanococktails can significantly reduce toxicity of dru...

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Detalles Bibliográficos
Autores principales: Pang, Lijun, Zhang, Lei, Zhou, Hong, Cao, Ling, Shao, Yueqin, Li, Tengyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931329/
https://www.ncbi.nlm.nih.gov/pubmed/35308794
http://dx.doi.org/10.3389/fchem.2022.844426