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The α7 Nicotinic Acetylcholine Receptor Agonist GTS-21 Improves Bacterial Clearance via Regulation of Monocyte Recruitment and Activity in Polymicrobial Septic Peritonitis

The cholinergic anti-inflammatory pathway has been identified as an effective pathway to modify inflammatory responses. Here, we verified that delayed administration with a selective α7nAChR agonist GTS-21 enables a more efficient elimination of the offending pathogens, diminished inflammatory respo...

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Detalles Bibliográficos
Autores principales:	Hu, Jian-nan, Liu, Ying, Liu, Shu-chang, Zhang, Teng, Chen, Gui-bing, Zhao, Jie, Ma, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931331/ https://www.ncbi.nlm.nih.gov/pubmed/35309361 http://dx.doi.org/10.3389/fimmu.2022.839290

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