Zafirlukast inhibits the growth of lung adenocarcinoma via inhibiting TMEM16A channel activity

Lung cancer has the highest mortality among cancers worldwide due to its high incidence and lack of the effective cures. We have previously demonstrated that the membrane ion channel TMEM16A is a potential drug target for the treatment of lung adenocarcinoma and have identified a pocket of inhibitor...

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Detalles Bibliográficos
Autores principales: Shi, Sai, Ma, Biao, Sun, Fude, Qu, Chang, Li, Gen, Shi, Donghong, Liu, Wenxin, Zhang, Hailin, An, Hailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931426/
https://www.ncbi.nlm.nih.gov/pubmed/35176281
http://dx.doi.org/10.1016/j.jbc.2022.101731

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