Cargando…

Antibodies binding diverse pertactin epitopes protect mice from Bordetella pertussis infection

Infection by the bacterium Bordetella pertussis continues to cause considerable morbidity and mortality worldwide. Many current acellular pertussis vaccines include the antigen pertactin, which has presumptive adhesive and immunomodulatory activities, but is rapidly lost from clinical isolates after...

Descripción completa

Detalles Bibliográficos
Autores principales: Silva, Rui P., DiVenere, Andrea M., Amengor, Dzifa, Maynard, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931430/
https://www.ncbi.nlm.nih.gov/pubmed/35151691
http://dx.doi.org/10.1016/j.jbc.2022.101715