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Fatty acid transport protein 2 interacts with ceramide synthase 2 to promote ceramide synthesis

Dihydroceramide is a lipid molecule generated via the action of (dihydro)ceramide synthases (CerSs), which use two substrates, namely sphinganine and fatty acyl-CoAs. Sphinganine is generated via the sequential activity of two integral membrane proteins located in the endoplasmic reticulum. Less is...

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Detalles Bibliográficos
Autores principales: Kim, Jiyoon L., Mestre, Beatriz, Malitsky, Sergey, Itkin, Maxim, Kupervaser, Meital, Futerman, Anthony H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931434/
https://www.ncbi.nlm.nih.gov/pubmed/35181339
http://dx.doi.org/10.1016/j.jbc.2022.101735