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Fatty acid transport protein 2 interacts with ceramide synthase 2 to promote ceramide synthesis
Dihydroceramide is a lipid molecule generated via the action of (dihydro)ceramide synthases (CerSs), which use two substrates, namely sphinganine and fatty acyl-CoAs. Sphinganine is generated via the sequential activity of two integral membrane proteins located in the endoplasmic reticulum. Less is...
Autores principales: | Kim, Jiyoon L., Mestre, Beatriz, Malitsky, Sergey, Itkin, Maxim, Kupervaser, Meital, Futerman, Anthony H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931434/ https://www.ncbi.nlm.nih.gov/pubmed/35181339 http://dx.doi.org/10.1016/j.jbc.2022.101735 |
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