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Shp2 suppresses fat accumulation in white adipose tissue by activating Wnt/β-catenin signaling following vertical sleeve gastrectomy in obese rats with type-2 diabetes
Adipogenesis and fat accumulation are closely associated with the development of obesity. Sleeve gastrectomy (SG) is an effective treatment for obesity and associated metabolic disorders. Leptin is downregulated after SG and Src homology phosphatase 2 (Shp2) has an important role in leptin signaling...
Autores principales: | Qi, Xiaoyang, Sun, Ziying, Li, Xugang, Jiao, Yuwen, Chen, Shuai, Song, Peng, Qian, Zhifen, Qian, Jun, Qiu, Xusheng, Tang, Liming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931631/ https://www.ncbi.nlm.nih.gov/pubmed/35340882 http://dx.doi.org/10.3892/etm.2022.11231 |
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