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Shp2 suppresses fat accumulation in white adipose tissue by activating Wnt/β-catenin signaling following vertical sleeve gastrectomy in obese rats with type-2 diabetes

Adipogenesis and fat accumulation are closely associated with the development of obesity. Sleeve gastrectomy (SG) is an effective treatment for obesity and associated metabolic disorders. Leptin is downregulated after SG and Src homology phosphatase 2 (Shp2) has an important role in leptin signaling...

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Detalles Bibliográficos
Autores principales: Qi, Xiaoyang, Sun, Ziying, Li, Xugang, Jiao, Yuwen, Chen, Shuai, Song, Peng, Qian, Zhifen, Qian, Jun, Qiu, Xusheng, Tang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931631/
https://www.ncbi.nlm.nih.gov/pubmed/35340882
http://dx.doi.org/10.3892/etm.2022.11231

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