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In Vivo Clearance of Apoptotic Debris From Tumor Xenografts Exposed to Chemically Modified Tetrac: Is There a Role for Thyroid Hormone Analogues in Efferocytosis?

Apoptosis is induced in cancer cells and tumor xenografts by the thyroid hormone analogue tetraiodothyroacetic acid (tetrac) or chemically modified forms of tetrac. The effect is initiated at a hormone receptor on the extracellular domain of plasma membrane integrin αvβ3. The tumor response to tetra...

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Detalles Bibliográficos
Autores principales:	Godugu, Kavitha, Mousa, Shaker A., Glinsky, Gennadi V., Lin, Hung-Yun, Davis, Paul J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931655/ https://www.ncbi.nlm.nih.gov/pubmed/35311239 http://dx.doi.org/10.3389/fendo.2022.745327

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